Gforge Advanced Server - Screensaver HTS LIMS - open-discussion http://forge.abcd.harvard.edu/gf/ Gforge Advanced Server RSS Nobel Prize winner Mello about RNAi Cor Lieftink <c.lieftink@nki.nl> Hi all, You can find a video of the presentation of Craig Mello about RNAi he did on 9 april 2007. Mello won the (shared) Nobel Prize for physiology or Medicine in 2006 for the discovery of RNai (2). The presentation is about 1 hour. Best regards, Cor   (1) view presentation (2) view Nobel Prize winner site RNAi overview and validation with singlesCor Lieftink <c.lieftink@nki.nl> Hi all, A recent article in "Nature Cell death and differentiation" (1) gives an overview of the use of RNAi in mammalian cells. A detail in the article I found interesting, was that the author claims that when validating with singles already two showing the phenotype is  "almost indisputable evidence that the knockdown and phenotype correlate strongly." Regards,  Cor (1) Wolters, N (et al) 2008. "From sequence to function: using RNAi to elucidate mechanisms of human disease". Nature Cell death and differentiation.